Bicytopenia and Abnormal Coagulation Profile in a Child with Influenza B: A RareCase Report
Keywords:
Influenza B, Child, Abnormal coagulation profile, BicytopeniaAbstract
Background:
Influenza B is a contagious respiratory illness that typically presents with acute febrile and respiratory symptoms. Hematologic abnormalities such as bicytopenia and coagulation disturbances are uncommon and may lead to diagnostic uncertainty.
Case Presentation:
We report a pediatric case of influenza B presenting with epistaxis, bicytopenia, and an abnormal coagulation profile during an outbreak. Laboratory evaluation revealed leukopenia, thrombocytopenia, and prolonged coagulation parameters. The diagnosis of influenza B was confirmed by nasopharyngeal swab polymerase chain reaction (PCR) testing. The patient was treated with oral oseltamivir, intravenous (IV) fluids, and paracetamol (acetaminophen). Clinical condition and laboratory abnormalities improved rapidly following antiviral therapy.
Conclusion:
Influenza B may present with transient hematologic abnormalities and coagulation disturbances, which can mimic more serious conditions. Awareness of such atypical presentations is essential to avoid unnecessary investigations, hospital admissions, and inappropriate antibiotic use. Further studies are needed to better characterize the hematologic spectrum associated with influenza B infection.
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Copyright (c) 2026 Muhammad Naveed Ashraf, Sania Ishtiaq Khan, John Twomey (Author)

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